The Molecular Startup Model
- Startup

The Molecular Startup Model

Many growth acceleration models for digital start-ups can be found in the literature. A noticeable one is the Monopoly scheme strategy by Peter Thiel, “Zero to One” theory.  It basically claims that you must stay in a monopoly situation as long as you can to succeed. One way to achieve this strategy is to follow the Digital Highway model by Julie Meyer that explains that “David must dance with Goliath”: essentially, the start-up (David) must use the worldwide distribution network and world-scale footprint of the large company (Goliath) to scale up its business.

The underlying philosophy is to conquer the broadest possible customer base in a short period of time. Meyer’s model clearly shows the accelerator component in the typical large company distribution channel. The point is then: how to apply Thiel’s approach in a fragmented market? For example, operating Meyer’s approach becomes a tricky game in the European market. Indeed, a European start-up must
tackle simultaneously two challenges, first overcome several hurdles (language, regulation, legal and cultural issues…), and secondly, that must be done on a limited time scale.

In this paper, we propose a growth model for start-ups, which guarantees a sustainable growth in a fragmented market in a reasonable time scale: the molecular start-up model.”

The Aggregator 2020 Deadline

The Aggregator 2020

What is really new in the old continent?

In 2014 during the SLUSH event3, Nicolas Brusson Bla Bla Car COO and co-founder, asked the question, “is Europe a big enough ocean?”. This is an important question for each European entrepreneur, so let’s consider some global figures regarding this market versus US markets. People: 743 versus 326 Million people for the USA; GDP: 17.3 trillion $ for Europe versus 16.8 trillion $ for the US and 100 biggest companies in the world 30 are European, and 40 are American… BUT regarding Technological companies, EU owns Europe capture only 4 % of the market capitalization versus 79% for the US…. which is a real paradox when we know the number and the qualities of research centers and the prestigious Universities’ that she counts. Finally, he sets clear the problem: “how do you address Europe as a Single Market? Or in another way: How do we build a European Company?

After recalling our old continent’s specificities and some rules that a promising startup should follow to become successful, we propose some growth strategy that holds the European constraints and fix the fragmentation issues.

Beyond the geographical and demographic differences, Europe is a juxtaposition of culture, education, tax, and regulation systems that constrain each entrepreneur — from collective entrepreneurship in Nordic countries including Germany to individual entrepreneurs cult and failures aversion in France.

This puzzle is the playground of each entrepreneur, and she/he must take into account to build her/his growth strategy.

One consequence is the drain to other continents such as the United States, China, and Asia…or at least the tendency to move your headquarter to California and leave your R&D resources in Europe (Symantec, TBC).

This situation is no better for Venture Capitalists who suffer from the same situation with a set of promising startups stuck in their native countries trying to expand their business to their European neighbors.

Whatever the angle you take to fix the problem, as an investor or entrepreneur, you reach the same conclusion, how to address a 700 M€ market fragmented into 27 pieces and define a sustainable growth strategy?

Peter Thiel, one of the founders of PayPal with Elon Musk, explains in “Zero to One” that to have a chance to survive or grow sustainably, you must stay in a monopoly on your market. What does it mean in a European context?

We have seen all the differences which divide this territory. Still, we also share some common things about our universities’ scientific and technical content and more or less a European lifestyle (compare to the middle east or Asia). This means that our entrepreneurs have the same scientific and technical background, and very close brains, in other words, can generate the same ideas.

This is also why Nicolas Brusson, BLABLA Car COO, found pretty quickly clones of his company in the close country of France and Italy, and wisely decided to convince his neighbors to merge their companies with his. This took him nine months, which represents a century at the startup time scale.

We already knew that the M&A scheme was an efficient growth model but not applicable to startup! From this, we learn two things; we can grow without money, and the best way to grow is not to buy another company but to convince another entrepreneur to join you …with her/his company. We build a company as we build a molecule by aggregation of atoms.

But we see immediately the problem generated by this approach as we ask entrepreneurs (at least at one over two) to give up her/his baby…which is somewhere against their DNA….

Another interesting thing is what large structures face while implementing their innovation strategy, especially with disruptive technologies. Some of them have identified this issue for a long time by creating an Open Innovation structure, but the gap between these two words seems wider than expected. Clayton M. Christensen shows that only the early players can expect to win at the end of the game in the case of disruptive technologies. What is the consequence of the large established companies?

The disruptive technologies market does not fit with the large company’s requirements as growth constraints and expectations. One way to tackle this challenge is to create a spin-off for the technology or acquire startups in the appropriate domain, as Christensen proves.

The molecular extension scheme:

Let’s take a project based on a cutting-edge technology application (atom) in European countries. What is the probability of finding the same or related project in one other of the 27 countries? I refuse to believe that this probability is zero. Assuming that we are in this case, we can call the “valence” of the project or the valence of atom the number of other projects (atoms) compatible (that can address the same market segment).

The idea is to build the best molecule as an aggregation of compatibles atoms.

This molecule has at least two interesting properties. First, it can grow simultaneously in each country. It has an atom, and second, it is more difficult to duplicate or copy it.


We call a molecular startup; a company built on the previous model, that is to say, a company built as an aggregation of two or more companies or startups addressing the same market and whose combination products or services deliver a consistent product or service. The simplest model is when you aggregate the same product or service in each country as Bla Bla car.

Advantages of a molecular scheme

Mainly three consequences:

  1. Geographical extension in several countries simultaneously in a short period of time which strengthens your monopoly position
  2. Make your product or service less duplicable or too expensive to do it
  3. Speed up your growth by parallelizing the process

Why must entrepreneurs speed up their growth?

For the above characteristic of common education, scientific maturity, and academic network… it is pretty clear that the probability of finding the same ideas in several European countries of Europe is quite high, a fortiori if the entry barriers are low.

How should entrepreneurs achieve this task?

  • Build an allies ecosystem – According to the European market structure and to overcome the fragmentation barriers, start-ups have two mains solutions. First, sign a deal with Goliath, whose structure and footprint make a worldwide framework to distribute their product or second approach to build a molecular extension scheme. The first step of the molecular extension scheme is to identify your allies. It’s a 3D space: Technical, Marketing, and financial.
  • Technical allies – This axis concerns only start-ups with a technological asset, and even if it’s often the easiest axis to deep dive for the entrepreneur, you have to keep in mind that there is always a technological barrier which can lock your product or new technology which can boost your productivity.
  • Industrial allies – This axis is usually underestimated because the entrepreneur’s first reaction is to divide the world between Customers and competitors. Still, this Manichean approach can cost you a lot. Another classic mistake is to only look for large companies as partners, expecting that it will become your customer sooner or later. The paradox is your better ally, maybe your first competitor or the company you see as an enemy. But unless this company makes the same product in the same street most of the time, its size and location are not a menace to your business…on a short time base. The question is, how can you identify this ally? Some tracks are: Use European organizations as EIT, EBN, or ECG.
  • Financial allies – After having done the first two steps, you have built a “Molecular start-up” each component or atom, being a start-up or SME in another European country, allowing you to parallelize your growth in several places on a short time period. Therefore, you will run the third by providing investors with a sustainable growth scheme in a fragmented market like Europe.

The Molecular Startup Model

According to the maturity stage and your financial capacities, you must deep dive into your potential allies’ ecosystem, always having in mind to keep a realistic product/market fit.


This approach came from five years of experience when I supported European start-ups at EIT Digital, one of the European Commission’s first European accelerators in 2010. So many times, I encountered the same project, the same start-up in almost all of the European incubators and accelerators of each country that it was clear that the classical growth model was based on geographical extension country by country or the silo approach could be improved. The European David always chooses to dance with Goliath or find another David to sustain her/his growth.

Jerome Chifflet  @jechifflet

Molecular Growth: Breakthrough Growth Models for Innovation

The Molecular Startup Model

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